Search on: SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS 
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Descriptor English:   Sodium Potassium Chloride Symporter Inhibitors 
Descriptor Spanish:   Inhibidores del Simportador de Cloruro Sódico y Cloruro Potásico 
Descriptor Portuguese:   Inibidores de Simportadores de Cloreto de Sódio e Potássio 
Synonyms English:   Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors
High Ceiling Diuretics
Loop Diuretics
Na-K-CL Symporter Inhibitors
Sodium Potassium Chloride Cotransporter Inhibitors
Bumetanide Sensitive Na K Cl Transporter Inhibitors
Ceiling Diuretics, High
Diuretics, High Ceiling
Diuretics, Loop
Inhibitors, Na-K-CL Symporter
Na K CL Symporter Inhibitors
Symporter Inhibitors, Na-K-CL  
Tree Number:   D27.505.519.562.906
D27.505.696.560.500.931
Definition English:   Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA. 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   51201 
Unique Identifier:   D049994 

Occurrence in VHL:
 

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